About Enhancer
| Enhancer ID: | E_03225 |
| Species: | Mus musculus |
| Position : | chr11:112634637-112637797   |
| Year: | 2017 |
| Title: | Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 28045957 |
| Tissue: | testis |
| Tissue Ontology ID: | UBERON:0000473 |
| Cell Source: | Sertoli cells |
| Cell Type: | Sertoli cell |
| Cell Ontology ID: | CL:0000216 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay, TF binding assay; Endogenous enhancer perturbation; In vivo functional validation |
| High Throughput Method: | RNA-seq |
| Low Throughput Method: | CRISPR knockout, RT-RT-qPCR, Immunofluorescence, ChIP-RT-qPCR; CRISPR-Cas9 endogenous deletion/editing; Mouse genetic deletion/knock-in |
About Target Gene
| Target gene : | Sox9 |
About TF
| TF name : | Sry |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Sry | AndrogenReceptor | netpath | 167 |
| Sry | Deactivation of the beta-catenin transactivating complex | reactome | 42 |
| Sry | Regulation of Androgen receptor activity | pid | 54 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03183 | chr11:112635500-112636792 | testis | Sertoli cell | NA |
Expression of Target Genes for the Enhancer