About Enhancer
| Enhancer ID: | E_03186 |
| Species: | Mus musculus |
| Position : | chr11:96200000-96202300   |
| Year: | 2014 |
| Title: | A regulatory network controls nephrocan expression and midgut patterning. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 25209250 |
| Tissue: | endoderm |
| Tissue Ontology ID: | UBERON:0000925 |
| Cell Source: | OMEGA-E |
| CVCL ID: | CVCL_2151 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Transgenic reporter assay; In vivo functional validation |
| Low Throughput Method: | Luciferase reporter assay, EMSA, Transgenic reporter assay, RT-RT-qPCR; In vivo phenotyping |
About Target Gene
| Target gene : | Nepn |
About TF
| TF name : | Rara |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Rara | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| Rara | FSH | netpath | 44 |
| Rara | IL3 | netpath | 84 |
| Rara | Nuclear Receptor transcription pathway | reactome | 51 |
| Rara | Retinoic acid receptors-mediated signaling | pid | 30 |
| Rara | RXR and RAR heterodimerization with other nuclear receptor | pid | 26 |
| Rara | Signaling by Retinoic Acid | reactome | 20 |
| Rara | Pathways in cancer | kegg | 321 |
| Rara | Acute myeloid leukemia | kegg | 53 |
| Rara | Hs_Tryptophan_metabolism_WP465_85055 | wikipathways | 45 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03187 | chr11:96201500-96202300 | endoderm | malignant cell | NA |
Expression of Target Genes for the Enhancer