About Enhancer
| Enhancer ID: | E_03161 |
| Species: | Mus musculus |
| Position : | chr8:120768340-120768887   |
| Year: | 2019 |
| Title: | An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 31406377 |
| Tissue: | bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | pre-cDC1 / mature cDC1 |
| Cell Type: | conventional dendritic cell type 1 |
| Experiment Type: | Stage-specific enhancer switching; genetic perturbation |
| High Throughput Method: | Single-cell RNA-seq; ATAC-seq |
| Low Throughput Method: | Genetic epistasis; enhancer-function analysis; flow cytometry |
About Target Gene
| Target gene : | Irf8 |
About TF
| TF name : | Batf3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Batf3 | Calcineurin-regulated NFAT-dependent transcription in lymphocytes | pid | 50 |
| Batf3 | Calcium signaling in the CD4+ TCR pathway | pid | 29 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer