Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03118
Species: Mus musculus
Position : chr6:122702344-122703335
Year: 2014
Title: Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  25223790
Tissue: embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: Nanog-GFP mouse embryonic stem cells
Cell Type: embryonic stem cell
Cell Ontology ID: CL:0002322
Experiment Type: Enhancer repression assay; functional perturbation assay; Enhancer activity assay
Low Throughput Method: TALE-KRAB enhancer repression; CRISPR/dCas9-KRAB enhancer repression; flow cytometry; RT-qPCR; Luciferase reporter assay
About Target Gene
Target gene : Nanog
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 13 found
Enhancer ID Position Tissue Cell Disease
E_05222 chr6:122696853-122708211 NA NA NA
E_05223 chr6:122696853-122708211 NA NA NA
E_05224 chr6:122696853-122708211 NA NA NA
E_05225 chr6:122696853-122708211 NA NA NA
E_05226 chr6:122696853-122708211 NA NA NA
E_03043 chr6:122698567-122721126 embryo mouse embryonic stem cell NA
E_03094 chr6:122700483-122702483 NA NA NA
E_03095 chr6:122700483-122702483 NA NA NA
E_03096 chr6:122700483-122702483 NA NA NA
E_03097 chr6:122700483-122702483 NA NA NA
E_03117 chr6:122702344-122703335 embryo embryonic stem cell NA
E_03119 chr6:122702344-122703335 epiblast (generic) epiblast cell NA
E_03120 chr6:122702344-122703335 epiblast (generic) epiblast cell NA
Expression of Target Genes for the Enhancer