About Enhancer
| Enhancer ID: | E_02_0912 |
| Species: | human |
| Position : | chr11:47363009-47364009   |
| Biosample name: | |
| Experiment class : | Low throughput |
| Enhancer type: | Enhancer |
| Disease: | Acute myeloid leukemia |
| Pubmed ID: | 24498324 |
| Enhancer experiment: | ChIP |
| Enhancer experiment description: | Using ChIP we focused on loci with more than 2-fold occupancy relative to control antibody. We dentified diffuse occupancy of CTCF with peaks involving amplicons -16.6 (downstream URE), -14.4 (Enhancer), and -11 (Element) as well as in the neighboring mplicons: -15.6, -13.7, -13.4, -13.3, -12.4 and also close to the promoter at -0.15. |
About Target gene
| Target gene : | SPI1(OF,PU.1,SFPI1,SPI-1,SPI-A) |
| Strong evidence: | -- |
| Less strong evidence: | RT-PCR,Western blot,Luciferase Reporter Assay |
| Target gene experiment description: | To conclude this part,CTCF and SMARCA5 co-occupy its newly validated target SPI1 using ChIP assay at the -14.4 Enhancer upon AZA-mediated DNA demethylation. |
About TF
| TF name : | -- |
| TF experiment: | -- |
| TF experiment description: | -- |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene