About Enhancer
| Enhancer ID: | E_02_0862 |
| Species: | human |
| Position : | chr21:42668000-42671000   |
| Biosample name: | |
| Experiment class : | Low+High throughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 26166704 |
| Enhancer experiment: | ChIP-seq,ChIP,GRO-seq |
| Enhancer experiment description: | Previous work from our lab and others established that a subgroup of ER-?/H3K27Ac co-bound enhancers (n=1,248,), exhibiting E2-upregulated eRNAs, high intensity of ER-? binding and close proximity to estrogen target genes, constitute the major E2-activated functional enhancers in MCF-7 cells, referred to as E2-induced "active enhancers" or eRNA+ enhancers. |
About Target gene
| Target gene : | TFF1(BCEI,D21S21,HP1.A,HPS2,pNR-2,pS2),TFF1(BCEI,D21S21,HP1.A,HPS2,pNR-2,pS2) |
| Strong evidence: | 3C |
| Less strong evidence: | ChIP-qPCR |
| Target gene experiment description: | Genome browser image showing the results of GRO-Seq and Pol II ChIP-Seq at TFF1 locus in the presence of condensin knockdown ( siNCAPG or siNCAPD3 ) vs siCTL transfected cell.;Genome browser image showing the results of GRO-Seq and Pol II ChIP-Seq at TFF1 locus in the presence of condensin knockdown ( siNCAPG or siNCAPD3 ) vs siCTL transfected cell. |
About TF
| TF name : | ---- |
| TF experiment: | -- |
| TF experiment description: | --;-- |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene