About Enhancer
| Enhancer ID: |
E_02_0828 |
| Species: |
human |
| Position :
|
chr1:67739940-67741075
  |
| Biosample name: |
|
| Experiment class :
|
low throughput |
| Enhancer type: |
enhancer |
| Disease: |
Ankylosing spondylitis |
| Pubmed ID: |
26916345
|
| Enhancer experiment: |
DNase I Hypersensitivity Assay |
| Enhancer experiment description: |
We identified a PRE (Chr1:6773994067741075) located 14.2 kb downstream of IL23R and 33.1 kb upstream of IL12RB2.This region is DNase I hypersensitive (in Th1-cells, but not Th17-cells) and exhibits TF binding (lymphoblastoid cell line; GM12878) and enhancer-associated H3K4me1 methylation (CD4+ CD25? IL-17A? T-cells; PMA and ionomycin-stimulated). |
About Target gene
| Target gene : |
IL23R(IL23R) |
| Strong evidence: |
-- |
| Less strong evidence: |
DNase I Hypersensitivity Assay |
| Target gene experiment description: |
We identified a PRE (Chr1:6773994067741075) located 14.2 kb downstream of IL23R and 33.1 kb upstream of IL12RB2.This region is DNase I hypersensitive (in Th1-cells, but not Th17-cells) and exhibits TF binding (lymphoblastoid cell line; GM12878) and enhancer-associated H3K4me1 methylation (CD4+ CD25? IL-17A? T-cells; PMA and ionomycin-stimulated). |
About TF
| TF name : |
-- |
| TF experiment: |
-- |
| TF experiment description: |
-- |
About Function
| Enhancer function : |
-- |
| Enhancer function experiment: |
-- |
Enhancer function
experiment description: |
-- |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs