About Enhancer
| Enhancer ID: | E_02_0755 |
| Species: | human |
| Position : | chr13:56243248-56243833   |
| Biosample name: | |
| Experiment class : | Low throughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 30008200 |
| Enhancer experiment: | ChIP |
| Enhancer experiment description: | In control cells, the enrichment of H3K27Ac, an active Enhancer marker, was significantly increased at the Neurog1 promoter, as well as other Enhancers, upon RA treatment. |
About Target gene
| Target gene : | Neurog1(AKA,Math4C,Neurod3,bHLHa6,ngn1) |
| Strong evidence: | -- |
| Less strong evidence: | ChIP-qPCR |
| Target gene experiment description: | Genome-wide CTCF occupancy patterns, which have been mapped across more than 100 mammalian cell types, re_x0002_vealed prominent CTCF binding to the -14.4 kb and -7.6 kb transcription start sites of Neurog1.We performed ChIP-qPCR analysis to validate the in vivo binding of CTCF in P19 cells, and observed strong occupancy of CTCF to these binding sites. |
About TF
| TF name : | Ctcf(MRD21) |
| TF experiment: | ChIP-qPCR |
| TF experiment description: | Genome-wide CTCF occupancy patterns, which have been mapped across more than 100 mammalian cell types, re_x0002_vealed prominent CTCF binding to the -14.4 kb and -7.6 kb transcription start sites of Neurog1.We performed ChIP-qPCR analysis to validate the in vivo binding of CTCF in P19 cells, and observed strong occupancy of CTCF to these binding sites. |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Ctcf | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| Ctcf | TGF_beta_Receptor | netpath | 220 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene