About Enhancer
| Enhancer ID: | E_02_0731 |
| Species: | human |
| Position : | chr12:49016308-49018308   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 33033055 |
| Enhancer experiment: | Western blots,chip-seq |
| Enhancer experiment description: | Trithorax-related (trr), MLL3 (KMT2C), and MLL4 (KMT2D) represent the branch of COMPASS family ly_x005f_x0002_sine methyltransferases responsible for catalyzing histone 3 lysine 4 monomethylation (H3K4me1) at enhancer chro_x0002_matin in Drosophila and mammals, respectively (Herzet al. 2012; Hu et al. 2013). |
About Target gene
| Target gene : | KMT2D |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Trithorax-related (trr), MLL3 (KMT2C), and MLL4 (KMT2D) represent the branch of COMPASS family ly_x005f_x0002_sine methyltransferases responsible for catalyzing histone 3 lysine 4 monomethylation (H3K4me1) at enhancer chro_x0002_matin in Drosophila and mammals, respectively (Herzet al. 2012; Hu et al. 2013). |
About TF
| TF name : | -- |
| TF experiment: | Western blots,chip-seq |
| TF experiment description: | Trithorax-related (trr), MLL3 (KMT2C), and MLL4 (KMT2D) represent the branch of COMPASS family ly_x005f_x0002_sine methyltransferases responsible for catalyzing histone 3 lysine 4 monomethylation (H3K4me1) at enhancer chro_x0002_matin in Drosophila and mammals, respectively (Herzet al. 2012; Hu et al. 2013). |
About Function
| Enhancer function : | Trithorax-related (trr), MLL3 (KMT2C), and MLL4 (KMT2D) represent the branch of COMPASS family ly_x005f_x0002_sine methyltransferases responsible for catalyzing histone 3 lysine 4 monomethylation (H3K4me1) at enhancer chro_x0002_matin in Drosophila and mammals, respectively (Herzet al. 2012; Hu et al. 2013). |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Trithorax-related (trr), MLL3 (KMT2C), and MLL4 (KMT2D) represent the branch of COMPASS family ly_x005f_x0002_sine methyltransferases responsible for catalyzing histone 3 lysine 4 monomethylation (H3K4me1) at enhancer chro_x0002_matin in Drosophila and mammals, respectively (Herzet al. 2012; Hu et al. 2013). |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene