About Enhancer
| Enhancer ID: | E_02_0722 |
| Species: | human |
| Position : | chr7:37903134-37905134   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Obesity |
| Pubmed ID: | 32657640 |
| Enhancer experiment: | qPCR,western blotting |
| Enhancer experiment description: | SFRP4 overexpression affected the expression of genes related to adipocyte differentiation, causing the upregulation of adiponectin and glucose transporter 4, and the downregulation of CCAAT/enhancer-binding protein-?, in both visceral and subcutaneous adipose tissue. |
About Target gene
| Target gene : | SFRP4 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | SFRP4 overexpression affected the expression of genes related to adipocyte differentiation, causing the upregulation of adiponectin and glucose transporter 4, and the downregulation of CCAAT/enhancer-binding protein-?, in both visceral and subcutaneous adipose tissue. |
About TF
| TF name : | -- |
| TF experiment: | qPCR,western blotting |
| TF experiment description: | SFRP4 overexpression affected the expression of genes related to adipocyte differentiation, causing the upregulation of adiponectin and glucose transporter 4, and the downregulation of CCAAT/enhancer-binding protein-?, in both visceral and subcutaneous adipose tissue. |
About Function
| Enhancer function : | SFRP4 overexpression affected the expression of genes related to adipocyte differentiation, causing the upregulation of adiponectin and glucose transporter 4, and the downregulation of CCAAT/enhancer-binding protein-?, in both visceral and subcutaneous adipose tissue. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
SFRP4 overexpression affected the expression of genes related to adipocyte differentiation, causing the upregulation of adiponectin and glucose transporter 4, and the downregulation of CCAAT/enhancer-binding protein-?, in both visceral and subcutaneous adipose tissue. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene