About Enhancer
| Enhancer ID: | E_02_0648 |
| Species: | human |
| Position : | chr3:133743131-133745131   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Breast cancer (breast cancer) |
| Pubmed ID: | 31391075 |
| Enhancer experiment: | Chip SEQ, ATAC SEQ, PCR, gel electrophoresis |
| Enhancer experiment description: | Nr5a1 gene (also called Sf-1 or Ad4BP) is a transcription factor (TF) belonging to the nuclear receptor superfamily. |
About Target gene
| Target gene : | TF,TBX19,PAX7,POU1F1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Nr5a1 gene (also called Sf-1 or Ad4BP) is a transcription factor (TF) belonging to the nuclear receptor superfamily.;Several TFs are known to promote pituitary stem cells diferentiation into a specifc endocrine lineage: POU1F1 is mandatory for the thyrotrope, somatotrope and lactotrope lineages , TBX19 for the corticotrope, PAX7 for the melanotrope and Nr5a1 for the gon_x005f_x0002_adotrope lineage.;Several TFs are known to promote pituitary stem cells diferentiation into a specifc endocrine lineage: POU1F1 is mandatory for the thyrotrope, somatotrope and lactotrope lineages , TBX19 for the corticotrope, PAX7 for the melanotrope and Nr5a1 for the gon_x005f_x0002_adotrope lineage.;Several TFs are known to promote pituitary stem cells diferentiation into a specifc endocrine lineage: POU1F1 is mandatory for the thyrotrope, somatotrope and lactotrope lineages , TBX19 for the corticotrope, PAX7 for the melanotrope and Nr5a1 for the gon_x005f_x0002_adotrope lineage. |
About TF
| TF name : | -- |
| TF experiment: | ChIP-seq,ATAC-seq,PCR,???? |
| TF experiment description: | Nr5a1 gene (also called Sf-1 or Ad4BP) is a transcription factor (TF) belonging to the nuclear receptor superfamily.;Several TFs are known to promote pituitary stem cells diferentiation into a specifc endocrine lineage: POU1F1 is mandatory for the thyrotrope, somatotrope and lactotrope lineages , TBX19 for the corticotrope, PAX7 for the melanotrope and Nr5a1 for the gon_x005f_x0002_adotrope lineage.;Several TFs are known to promote pituitary stem cells diferentiation into a specifc endocrine lineage: POU1F1 is mandatory for the thyrotrope, somatotrope and lactotrope lineages , TBX19 for the corticotrope, PAX7 for the melanotrope and Nr5a1 for the gon_x005f_x0002_adotrope lineage.;Several TFs are known to promote pituitary stem cells diferentiation into a specifc endocrine lineage: POU1F1 is mandatory for the thyrotrope, somatotrope and lactotrope lineages , TBX19 for the corticotrope, PAX7 for the melanotrope and Nr5a1 for the gon_x005f_x0002_adotrope lineage. |
About Function
| Enhancer function : | Nr5a1 gene (also called Sf-1 or Ad4BP) is a transcription factor (TF) belonging to the nuclear receptor superfamily. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Nr5a1 gene (also called Sf-1 or Ad4BP) is a transcription factor (TF) belonging to the nuclear receptor superfamily. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene