About Enhancer
| Enhancer ID: | E_02_0597 |
| Species: | human |
| Position : | chr3:147382975-147384975   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Hepatocellular carcinoma |
| Pubmed ID: | 33097694 |
| Enhancer experiment: | Transfection of shRNA, DNA methylation analysis, RNA extraction and quantitative reverse transcription polymerase chain reaction (QRT PCR), Western blot analysis, chromatin immunoprecipitation discovery, flow cytometry |
| Enhancer experiment description: | Inactivation of tumor suppressor gene played critical roles in the development and progression of human hepatocellular carcinoma (HCC). Zic family member 4 (ZIC4) is transcription factor and plays an important role in the developmental process. |
About Target gene
| Target gene : | ZIC4 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Inactivation of tumor suppressor gene played critical roles in the development and progression of human hepatocellular carcinoma (HCC). Zic family member 4 (ZIC4) is transcription factor and plays an important role in the developmental process. |
About TF
| TF name : | -- |
| TF experiment: | ?? shRNA?DNA??????RNA????????-???????qRT-PCR????????????????????????? |
| TF experiment description: | Inactivation of tumor suppressor gene played critical roles in the development and progression of human hepatocellular carcinoma (HCC). Zic family member 4 (ZIC4) is transcription factor and plays an important role in the developmental process. |
About Function
| Enhancer function : | Inactivation of tumor suppressor gene played critical roles in the development and progression of human hepatocellular carcinoma (HCC). Zic family member 4 (ZIC4) is transcription factor and plays an important role in the developmental process. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Inactivation of tumor suppressor gene played critical roles in the development and progression of human hepatocellular carcinoma (HCC). Zic family member 4 (ZIC4) is transcription factor and plays an important role in the developmental process. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene