About Enhancer
| Enhancer ID: | E_02_0596 |
| Species: | human |
| Position : | chr5:176808090-176810090   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Colon cancer |
| Pubmed ID: | 33126652 |
| Enhancer experiment: | Immunohistochemical staining, quantification, RT-PCR quantification, extraction of total and chromatin bound proteins, Western blotting and antibodies, luciferase promoter activity assay, CO immunoprecipitation |
| Enhancer experiment description: | Our data support the hypothesis that O-GlcNAcylation could represent one link between nutrition and epigenetic downregulation of key tumor suppressor genes governing colon carcinogenesis including UNC5A. |
About Target gene
| Target gene : | UNC5A |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Our data support the hypothesis that O-GlcNAcylation could represent one link between nutrition and epigenetic downregulation of key tumor suppressor genes governing colon carcinogenesis including UNC5A. |
About TF
| TF name : | -- |
| TF experiment: | ????????????RT-PCR?????????????????????????????????????????????? |
| TF experiment description: | Our data support the hypothesis that O-GlcNAcylation could represent one link between nutrition and epigenetic downregulation of key tumor suppressor genes governing colon carcinogenesis including UNC5A. |
About Function
| Enhancer function : | Our data support the hypothesis that O-GlcNAcylation could represent one link between nutrition and epigenetic downregulation of key tumor suppressor genes governing colon carcinogenesis including UNC5A. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Our data support the hypothesis that O-GlcNAcylation could represent one link between nutrition and epigenetic downregulation of key tumor suppressor genes governing colon carcinogenesis including UNC5A. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene