About Enhancer
| Enhancer ID: | E_02_0591 |
| Species: | human |
| Position : | chr6:89923787-89925787   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Cancer |
| Pubmed ID: | 33144667 |
| Enhancer experiment: | Sanger sequencing and data analysis, luciferase assay, Western blot, rgfp966 inhibitor treatment |
| Enhancer experiment description: | The transcription factor BACH2 functions as a pervasive regulator of T cell differentiation, promoting development of CD4 T+reg cells and suppressing the effector functions of multiple effector T cell (Teff) lineages. |
About Target gene
| Target gene : | BACH2(BTBD25,IMD60) |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | The transcription factor BACH2 functions as a pervasive regulator of T cell differentiation, promoting development of CD4 T+reg cells and suppressing the effector functions of multiple effector T cell (Teff) lineages. |
About TF
| TF name : | -- |
| TF experiment: | ???????????????????????RGFP966 ????? |
| TF experiment description: | The transcription factor BACH2 functions as a pervasive regulator of T cell differentiation, promoting development of CD4 T+reg cells and suppressing the effector functions of multiple effector T cell (Teff) lineages. |
About Function
| Enhancer function : | The transcription factor BACH2 functions as a pervasive regulator of T cell differentiation, promoting development of CD4 T+reg cells and suppressing the effector functions of multiple effector T cell (Teff) lineages. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
The transcription factor BACH2 functions as a pervasive regulator of T cell differentiation, promoting development of CD4 T+reg cells and suppressing the effector functions of multiple effector T cell (Teff) lineages. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene