About Enhancer
| Enhancer ID: |
E_02_0586 |
| Species: |
mouse |
| Position :
|
chr6:47504488-47506488
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
-- |
| Pubmed ID: |
33187138
|
| Enhancer experiment: |
MicroRNA expression analysis using microarrays, microRNA quantification, transient transfection, reverse transcriptase and real-time quantitative fluorescent PCR (RT qPCR), luciferase reporter assays |
| Enhancer experiment description: |
Ezh2 is a catalytic subunit of the polycomb repressive complex 2 (PRC2) which mediates epigenetic gene silencing through depositing the mark histone H3 lysine 27 trimethylation (H3K27me3) at target genomic sequences. |
About Target gene
| Target gene : |
Ezh2 |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Ezh2 is a catalytic subunit of the polycomb repressive complex 2 (PRC2) which mediates epigenetic gene silencing through depositing the mark histone H3 lysine 27 trimethylation (H3K27me3) at target genomic sequences. |
About TF
| TF name : |
-- |
| TF experiment: |
??????MicroRNA???????RNA????????????????????? PCR ?RT-qPCR???????????? |
| TF experiment description: |
Ezh2 is a catalytic subunit of the polycomb repressive complex 2 (PRC2) which mediates epigenetic gene silencing through depositing the mark histone H3 lysine 27 trimethylation (H3K27me3) at target genomic sequences. |
About Function
| Enhancer function : |
Ezh2 is a catalytic subunit of the polycomb repressive complex 2 (PRC2) which mediates epigenetic gene silencing through depositing the mark histone H3 lysine 27 trimethylation (H3K27me3) at target genomic sequences. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
Ezh2 is a catalytic subunit of the polycomb repressive complex 2 (PRC2) which mediates epigenetic gene silencing through depositing the mark histone H3 lysine 27 trimethylation (H3K27me3) at target genomic sequences. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs