About Enhancer
| Enhancer ID: |
E_02_0574 |
| Species: |
human |
| Position :
|
chr7:116521979-116523979
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Amyotrophic lateral sclerosis |
| Pubmed ID: |
33264630
|
| Enhancer experiment: |
Immunoblotting, fluorescent quantitative PCR (RT-PCR), immunocytochemistry, live cell imaging |
| Enhancer experiment description: |
CAV1 and CAV2 organize membrane lipid rafts (MLRs) important for cell signaling and neuronal survival, and overexpression of CAV1 ameliorates ALS phenotypes in vivo. |
About Target gene
| Target gene : |
CAV1 |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
CAV1 and CAV2 organize membrane lipid rafts (MLRs) important for cell signaling and neuronal survival, and overexpression of CAV1 ameliorates ALS phenotypes in vivo. |
About TF
| TF name : |
-- |
| TF experiment: |
????????? PCR?RT-PCR?????????????? |
| TF experiment description: |
CAV1 and CAV2 organize membrane lipid rafts (MLRs) important for cell signaling and neuronal survival, and overexpression of CAV1 ameliorates ALS phenotypes in vivo. |
About Function
| Enhancer function : |
CAV1 and CAV2 organize membrane lipid rafts (MLRs) important for cell signaling and neuronal survival, and overexpression of CAV1 ameliorates ALS phenotypes in vivo. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
CAV1 and CAV2 organize membrane lipid rafts (MLRs) important for cell signaling and neuronal survival, and overexpression of CAV1 ameliorates ALS phenotypes in vivo. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs