About Enhancer
| Enhancer ID: |
E_02_0564 |
| Species: |
human |
| Position :
|
chr19:39383229-39385229
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Cancer |
| Pubmed ID: |
33376128
|
| Enhancer experiment: |
CRISPR / cas9 assisted GFP labeling, chip SEQ, QRT PCR and RNA SEQ, immunostaining for Western blotting |
| Enhancer experiment description: |
The RNA polymerase II (RNAPII) associated factor 1 complex (Paf1C) plays critical roles in modulating the release of paused RNAPII into productive elongation. |
About Target gene
| Target gene : |
PAF1 |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
The RNA polymerase II (RNAPII) associated factor 1 complex (Paf1C) plays critical roles in modulating the release of paused RNAPII into productive elongation. |
About TF
| TF name : |
-- |
| TF experiment: |
CRISPR/Cas9 ?? GFP ???ChIP-seq?qRT-PCR ? RNA-seq?????????? |
| TF experiment description: |
The RNA polymerase II (RNAPII) associated factor 1 complex (Paf1C) plays critical roles in modulating the release of paused RNAPII into productive elongation. |
About Function
| Enhancer function : |
The RNA polymerase II (RNAPII) associated factor 1 complex (Paf1C) plays critical roles in modulating the release of paused RNAPII into productive elongation. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
The RNA polymerase II (RNAPII) associated factor 1 complex (Paf1C) plays critical roles in modulating the release of paused RNAPII into productive elongation. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs