About Enhancer
| Enhancer ID: | E_02_0490 |
| Species: | human |
| Position : | chr1:180629337-180631337   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Leukemia |
| Pubmed ID: | 30096897 |
| Enhancer experiment: | PCR |
| Enhancer experiment description: | The E-MLVs use the CAT-1 receptor [4], and all X/P-MLVs use the XPR1 receptor [5,6,7]. There are functionally distinct XPR1 variants in the genus Mus, but the majority of mouse strains carry Xpr1n, which allows for the infection of P-MLVs but not X-MLVs [8]. |
About Target gene
| Target gene : | XPR1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | The E-MLVs use the CAT-1 receptor [4], and all X/P-MLVs use the XPR1 receptor [5,6,7]. There are functionally distinct XPR1 variants in the genus Mus, but the majority of mouse strains carry Xpr1n, which allows for the infection of P-MLVs but not X-MLVs [8]. |
About TF
| TF name : | -- |
| TF experiment: | PCR |
| TF experiment description: | The E-MLVs use the CAT-1 receptor [4], and all X/P-MLVs use the XPR1 receptor [5,6,7]. There are functionally distinct XPR1 variants in the genus Mus, but the majority of mouse strains carry Xpr1n, which allows for the infection of P-MLVs but not X-MLVs [8]. |
About Function
| Enhancer function : | The E-MLVs use the CAT-1 receptor [4], and all X/P-MLVs use the XPR1 receptor [5,6,7]. There are functionally distinct XPR1 variants in the genus Mus, but the majority of mouse strains carry Xpr1n, which allows for the infection of P-MLVs but not X-MLVs [8]. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
The E-MLVs use the CAT-1 receptor [4], and all X/P-MLVs use the XPR1 receptor [5,6,7]. There are functionally distinct XPR1 variants in the genus Mus, but the majority of mouse strains carry Xpr1n, which allows for the infection of P-MLVs but not X-MLVs [8]. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene