About Enhancer
| Enhancer ID: |
E_02_0476 |
| Species: |
human |
| Position :
|
chr1:145667850-145669850
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Hyperuricemia |
| Pubmed ID: |
30124855
|
| Enhancer experiment: |
Quantitative PCR, immunoblot analysis, chip PCR, statistical analysis, Weston blot |
| Enhancer experiment description: |
siRNA depletion of HNF4A reduced endogenous PDZK1 expression in HepG2 cells. |
About Target gene
| Target gene : |
PDZK1,HNF4A(FRTS4,HNF4,HNF4a7,HNF4a8,HNF4a9,HNF4alpha,MODY,MODY1,NR2A1,NR2A21,TCF,TCF14) |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
siRNA depletion of HNF4A reduced endogenous PDZK1 expression in HepG2 cells. ;siRNA depletion of HNF4A reduced endogenous PDZK1 expression in HepG2 cells. |
About TF
| TF name : |
-- |
| TF experiment: |
Quantitative PCR,Immunoblot analysis, ChIP-PCR,????,weston blot |
| TF experiment description: |
siRNA depletion of HNF4A reduced endogenous PDZK1 expression in HepG2 cells. ;siRNA depletion of HNF4A reduced endogenous PDZK1 expression in HepG2 cells. |
About Function
| Enhancer function : |
siRNA depletion of HNF4A reduced endogenous PDZK1 expression in HepG2 cells. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
siRNA depletion of HNF4A reduced endogenous PDZK1 expression in HepG2 cells. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs