About Enhancer
| Enhancer ID: | E_02_0470 |
| Species: | mouse |
| Position : | chr17:71648774-71650774   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 30127357 |
| Enhancer experiment: | Chip SEQ, immunofluorescence staining, RT qPCR, Weston blot |
| Enhancer experiment description: | Structural maintenance of chromosomes hinge domain contain- ing 1 (Smchd1) is a noncanonical SMC protein12 that is similar to the canonical SMC proteins13 15 in that it dimerizes and interacts with nucleic acids through its hinge domain 16,17 . At all Smchd1 targets, chromosome conformation at differ- ent scales plays a role in regulating gene expression. |
About Target gene
| Target gene : | Smchd1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Structural maintenance of chromosomes hinge domain contain- ing 1 (Smchd1) is a noncanonical SMC protein12 that is similar to the canonical SMC proteins13 15 in that it dimerizes and interacts with nucleic acids through its hinge domain 16,17 . At all Smchd1 targets, chromosome conformation at differ- ent scales plays a role in regulating gene expression. |
About TF
| TF name : | -- |
| TF experiment: | ChIP-seq,??????,RT-qPCR,weston blot |
| TF experiment description: | Structural maintenance of chromosomes hinge domain contain- ing 1 (Smchd1) is a noncanonical SMC protein12 that is similar to the canonical SMC proteins13 15 in that it dimerizes and interacts with nucleic acids through its hinge domain 16,17 . At all Smchd1 targets, chromosome conformation at differ- ent scales plays a role in regulating gene expression. |
About Function
| Enhancer function : | Structural maintenance of chromosomes hinge domain contain- ing 1 (Smchd1) is a noncanonical SMC protein12 that is similar to the canonical SMC proteins13 15 in that it dimerizes and interacts with nucleic acids through its hinge domain 16,17 . At all Smchd1 targets, chromosome conformation at differ- ent scales plays a role in regulating gene expression. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Structural maintenance of chromosomes hinge domain contain- ing 1 (Smchd1) is a noncanonical SMC protein12 that is similar to the canonical SMC proteins13 15 in that it dimerizes and interacts with nucleic acids through its hinge domain 16,17 . At all Smchd1 targets, chromosome conformation at differ- ent scales plays a role in regulating gene expression. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene