About Enhancer
| Enhancer ID: | E_02_0466 |
| Species: | human |
| Position : | chr6:31572566-31574566   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Mammary cancer |
| Pubmed ID: | 30132536 |
| Enhancer experiment: | ATP quantification, Weston blot, statistical analysis |
| Enhancer experiment description: | TRAIL has reduced toxicicity compared with other members of the tumor necrosis factor (TNF) protein family, such as TNF? and Fas ligand (CD95L) (3). Pre-clinical trials have determined that TRAIL effectively inhibits tumor growth without inducing toxicity in both mice and non-human primates (4,5). |
About Target gene
| Target gene : | TNF |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | TRAIL has reduced toxicicity compared with other members of the tumor necrosis factor (TNF) protein family, such as TNF? and Fas ligand (CD95L) (3). Pre-clinical trials have determined that TRAIL effectively inhibits tumor growth without inducing toxicity in both mice and non-human primates (4,5). |
About TF
| TF name : | -- |
| TF experiment: | ATP quantification,weston blot,???? |
| TF experiment description: | TRAIL has reduced toxicicity compared with other members of the tumor necrosis factor (TNF) protein family, such as TNF? and Fas ligand (CD95L) (3). Pre-clinical trials have determined that TRAIL effectively inhibits tumor growth without inducing toxicity in both mice and non-human primates (4,5). |
About Function
| Enhancer function : | TRAIL has reduced toxicicity compared with other members of the tumor necrosis factor (TNF) protein family, such as TNF? and Fas ligand (CD95L) (3). Pre-clinical trials have determined that TRAIL effectively inhibits tumor growth without inducing toxicity in both mice and non-human primates (4,5). |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
TRAIL has reduced toxicicity compared with other members of the tumor necrosis factor (TNF) protein family, such as TNF? and Fas ligand (CD95L) (3). Pre-clinical trials have determined that TRAIL effectively inhibits tumor growth without inducing toxicity in both mice and non-human primates (4,5). |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene