About Enhancer
| Enhancer ID: | E_02_0464 |
| Species: | human |
| Position : | chr21:37362767-37364767   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Mental retardation, microcephaly |
| Pubmed ID: | 30137413 |
| Enhancer experiment: | Chip SEQ, RT qPCR, statistical analysis, Weston blot, gene knockdown |
| Enhancer experiment description: | DYRK1A, dual-specificity tyrosine phosphorylation-regulated kinase 1A, which is linked to mental retardation and microcephaly, is a member of the CMGC group of kinases. |
About Target gene
| Target gene : | DYRK1A |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | DYRK1A, dual-specificity tyrosine phosphorylation-regulated kinase 1A, which is linked to mental retardation and microcephaly, is a member of the CMGC group of kinases. |
About TF
| TF name : | -- |
| TF experiment: | ChIP-Seq,RT-qPCR,????,weston blot,???? |
| TF experiment description: | DYRK1A, dual-specificity tyrosine phosphorylation-regulated kinase 1A, which is linked to mental retardation and microcephaly, is a member of the CMGC group of kinases. |
About Function
| Enhancer function : | DYRK1A, dual-specificity tyrosine phosphorylation-regulated kinase 1A, which is linked to mental retardation and microcephaly, is a member of the CMGC group of kinases. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
DYRK1A, dual-specificity tyrosine phosphorylation-regulated kinase 1A, which is linked to mental retardation and microcephaly, is a member of the CMGC group of kinases. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene