About Enhancer
| Enhancer ID: |
E_02_0462 |
| Species: |
mouse |
| Position :
|
chr18:38066274-38068274
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Leukemia |
| Pubmed ID: |
30139328
|
| Enhancer experiment: |
PCR, pro SEQ, gro SEQ, nascent RNA sequencing analysis, chip seq |
| Enhancer experiment description: |
Applied to wildtype and histone deacetylase 3 (Hdac3) knockout mouse livers, NRSA showed that HDAC3 regulates RNA polymerase recruitment through both proximal (promoter) and distal (enhancer) regulatory elements. |
About Target gene
| Target gene : |
Hdac3 |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Applied to wildtype and histone deacetylase 3 (Hdac3) knockout mouse livers, NRSA showed that HDAC3 regulates RNA polymerase recruitment through both proximal (promoter) and distal (enhancer) regulatory elements. |
About TF
| TF name : |
-- |
| TF experiment: |
PCR,PRO-seq,GRO-seq,??RNA????,ChIP-seq |
| TF experiment description: |
Applied to wildtype and histone deacetylase 3 (Hdac3) knockout mouse livers, NRSA showed that HDAC3 regulates RNA polymerase recruitment through both proximal (promoter) and distal (enhancer) regulatory elements. |
About Function
| Enhancer function : |
Applied to wildtype and histone deacetylase 3 (Hdac3) knockout mouse livers, NRSA showed that HDAC3 regulates RNA polymerase recruitment through both proximal (promoter) and distal (enhancer) regulatory elements. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
Applied to wildtype and histone deacetylase 3 (Hdac3) knockout mouse livers, NRSA showed that HDAC3 regulates RNA polymerase recruitment through both proximal (promoter) and distal (enhancer) regulatory elements. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs