About Enhancer
| Enhancer ID: | E_02_0450 |
| Species: | human |
| Position : | chr10:88950948-88952948   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Atherosclerosis, coronary heart disease, obesity |
| Pubmed ID: | 30154726 |
| Enhancer experiment: | Real time PCR, Weston blot, statistical analysis, and immunofluorescence staining |
| Enhancer experiment description: | The mRNA expression of CCAAT/enhancer-binding protein ? (C/EBP?) and fatty acid synthase (FAS), FAS activity, and the content of glycerol and triglyceride (TG) were decreased in the muscle by 509.6 and 1007.5 mg/kg VC diets. |
About Target gene
| Target gene : | FAS |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | The mRNA expression of CCAAT/enhancer-binding protein ? (C/EBP?) and fatty acid synthase (FAS), FAS activity, and the content of glycerol and triglyceride (TG) were decreased in the muscle by 509.6 and 1007.5 mg/kg VC diets. |
About TF
| TF name : | -- |
| TF experiment: | real-time PCR,weston blot,????,?????? |
| TF experiment description: | The mRNA expression of CCAAT/enhancer-binding protein ? (C/EBP?) and fatty acid synthase (FAS), FAS activity, and the content of glycerol and triglyceride (TG) were decreased in the muscle by 509.6 and 1007.5 mg/kg VC diets. |
About Function
| Enhancer function : | The mRNA expression of CCAAT/enhancer-binding protein ? (C/EBP?) and fatty acid synthase (FAS), FAS activity, and the content of glycerol and triglyceride (TG) were decreased in the muscle by 509.6 and 1007.5 mg/kg VC diets. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
The mRNA expression of CCAAT/enhancer-binding protein ? (C/EBP?) and fatty acid synthase (FAS), FAS activity, and the content of glycerol and triglyceride (TG) were decreased in the muscle by 509.6 and 1007.5 mg/kg VC diets. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene