About Enhancer
| Enhancer ID: | E_02_0441 |
| Species: | human |
| Position : | chr10:88950916-88952916   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Obesity, diabetes, hypertension, cvd |
| Pubmed ID: | 30173509 |
| Enhancer experiment: | Statistical analysis, Weston blot |
| Enhancer experiment description: | The antibodies for phospho-AMP-activated protein kinase alpha (p-AMPK?,73 Thr 172), AMPK?, phospho-acetyl-CoA carboxylase (p-ACC, Ser 79), ACC, fatty acid74 synthase (FAS), elongation of very long-chain fatty acids protein 6 (ELOVL 6), stearoyl-CoA75 desaturase-1 (SCD1), peroxisome proliferator-activated receptor gamma (PPAR-?),76 CCAAT/enhancer-binding protein alpha (C/EBP-?), TATA-binding protein (TBP), and ?-77 actin were from Cell Signaling Technology (Danvers, MA, USA). |
About Target gene
| Target gene : | FAS,GPAM |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | The antibodies for phospho-AMP-activated protein kinase alpha (p-AMPK?,73 Thr 172), AMPK?, phospho-acetyl-CoA carboxylase (p-ACC, Ser 79), ACC, fatty acid74 synthase (FAS), elongation of very long-chain fatty acids protein 6 (ELOVL 6), stearoyl-CoA75 desaturase-1 (SCD1), peroxisome proliferator-activated receptor gamma (PPAR-?),76 CCAAT/enhancer-binding protein alpha (C/EBP-?), TATA-binding protein (TBP), and ?-77 actin were from Cell Signaling Technology (Danvers, MA, USA).;The antibodies for phospho-AMP-activated protein kinase alpha (p-AMPK?,73 Thr 172), AMPK?, phospho-acetyl-CoA carboxylase (p-ACC, Ser 79), ACC, fatty acid74 synthase (FAS), elongation of very long-chain fatty acids protein 6 (ELOVL 6), stearoyl-CoA75 desaturase-1 (SCD1), peroxisome proliferator-activated receptor gamma (PPAR-?),76 CCAAT/enhancer-binding protein alpha (C/EBP-?), TATA-binding protein (TBP), and ?-77 actin were from Cell Signaling Technology (Danvers, MA, USA). |
About TF
| TF name : | -- |
| TF experiment: | ????,weston blot |
| TF experiment description: | The antibodies for phospho-AMP-activated protein kinase alpha (p-AMPK?,73 Thr 172), AMPK?, phospho-acetyl-CoA carboxylase (p-ACC, Ser 79), ACC, fatty acid74 synthase (FAS), elongation of very long-chain fatty acids protein 6 (ELOVL 6), stearoyl-CoA75 desaturase-1 (SCD1), peroxisome proliferator-activated receptor gamma (PPAR-?),76 CCAAT/enhancer-binding protein alpha (C/EBP-?), TATA-binding protein (TBP), and ?-77 actin were from Cell Signaling Technology (Danvers, MA, USA).;The antibodies for phospho-AMP-activated protein kinase alpha (p-AMPK?,73 Thr 172), AMPK?, phospho-acetyl-CoA carboxylase (p-ACC, Ser 79), ACC, fatty acid74 synthase (FAS), elongation of very long-chain fatty acids protein 6 (ELOVL 6), stearoyl-CoA75 desaturase-1 (SCD1), peroxisome proliferator-activated receptor gamma (PPAR-?),76 CCAAT/enhancer-binding protein alpha (C/EBP-?), TATA-binding protein (TBP), and ?-77 actin were from Cell Signaling Technology (Danvers, MA, USA). |
About Function
| Enhancer function : | The antibodies for phospho-AMP-activated protein kinase alpha (p-AMPK?,73 Thr 172), AMPK?, phospho-acetyl-CoA carboxylase (p-ACC, Ser 79), ACC, fatty acid74 synthase (FAS), elongation of very long-chain fatty acids protein 6 (ELOVL 6), stearoyl-CoA75 desaturase-1 (SCD1), peroxisome proliferator-activated receptor gamma (PPAR-?),76 CCAAT/enhancer-binding protein alpha (C/EBP-?), TATA-binding protein (TBP), and ?-77 actin were from Cell Signaling Technology (Danvers, MA, USA). |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
The antibodies for phospho-AMP-activated protein kinase alpha (p-AMPK?,73 Thr 172), AMPK?, phospho-acetyl-CoA carboxylase (p-ACC, Ser 79), ACC, fatty acid74 synthase (FAS), elongation of very long-chain fatty acids protein 6 (ELOVL 6), stearoyl-CoA75 desaturase-1 (SCD1), peroxisome proliferator-activated receptor gamma (PPAR-?),76 CCAAT/enhancer-binding protein alpha (C/EBP-?), TATA-binding protein (TBP), and ?-77 actin were from Cell Signaling Technology (Danvers, MA, USA). |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene