About Enhancer
| Enhancer ID: | E_02_0426 |
| Species: | human |
| Position : | chr14:92041650-92043650   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Neurodegenerative diseases, alzheimer's disease |
| Pubmed ID: | 30205834 |
| Enhancer experiment: | RT qPCR, Weston BOT, gene knockdown |
| Enhancer experiment description: | Methods We first examined a role for intracellular astrocytic responses in a Drosophila model for Spinocerebellar ataxia type 3 (SCA3, also known as Machado Joseph disease), a disease caused by expansion of the polyglutamine (polyQ) stretch in the ATXN3 gene. |
About Target gene
| Target gene : | ATXN3 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Methods We first examined a role for intracellular astrocytic responses in a Drosophila model for Spinocerebellar ataxia type 3 (SCA3, also known as Machado Joseph disease), a disease caused by expansion of the polyglutamine (polyQ) stretch in the ATXN3 gene. |
About TF
| TF name : | -- |
| TF experiment: | RT-qPCR,weston bot,???? |
| TF experiment description: | Methods We first examined a role for intracellular astrocytic responses in a Drosophila model for Spinocerebellar ataxia type 3 (SCA3, also known as Machado Joseph disease), a disease caused by expansion of the polyglutamine (polyQ) stretch in the ATXN3 gene. |
About Function
| Enhancer function : | Methods We first examined a role for intracellular astrocytic responses in a Drosophila model for Spinocerebellar ataxia type 3 (SCA3, also known as Machado Joseph disease), a disease caused by expansion of the polyglutamine (polyQ) stretch in the ATXN3 gene. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Methods We first examined a role for intracellular astrocytic responses in a Drosophila model for Spinocerebellar ataxia type 3 (SCA3, also known as Machado Joseph disease), a disease caused by expansion of the polyglutamine (polyQ) stretch in the ATXN3 gene. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene