About Enhancer
| Enhancer ID: | E_02_0412 |
| Species: | human |
| Position : | chr4:105143201-105145201   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | B cell lymphoma |
| Pubmed ID: | 30274972 |
| Enhancer experiment: | ELISA and ELISPOT,Flow cytometry analysis,Histology and immunohistochemistry,Genomic DNA and RNA extraction,DNA seq,quantification of methylation,ChIP,Quantitative real-time PCR,hMeDIP-seq,RNA-seq |
| Enhancer experiment description: | Hence TET2 plays a critical role in the GC reaction and its loss of function results in lymphomagenesis through failure to activate genes linked to GC exit signals. |
About Target gene
| Target gene : | TET2(Ayu17-449,E130014J05Rik,mKIAA1546) |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Hence TET2 plays a critical role in the GC reaction and its loss of function results in lymphomagenesis through failure to activate genes linked to GC exit signals. |
About TF
| TF name : | -- |
| TF experiment: | ELISA and ELISPOT,Flow cytometry analysis,Histology and immunohistochemistry,Genomic DNA and RNA extraction,DNA seq,quantification of methylation,ChIP,Quantitative real-time PCR,hMeDIP-seq,RNA-seq |
| TF experiment description: | Hence TET2 plays a critical role in the GC reaction and its loss of function results in lymphomagenesis through failure to activate genes linked to GC exit signals. |
About Function
| Enhancer function : | Hence TET2 plays a critical role in the GC reaction and its loss of function results in lymphomagenesis through failure to activate genes linked to GC exit signals. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Hence TET2 plays a critical role in the GC reaction and its loss of function results in lymphomagenesis through failure to activate genes linked to GC exit signals. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene