About Enhancer
| Enhancer ID: | E_02_0410 |
| Species: | human |
| Position : | chr7:129609040-129611040   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Obesity and type 2 diabetes |
| Pubmed ID: | 30284014 |
| Enhancer experiment: | RNA-Seq?ChIP-Seq?qPCR?TSS |
| Enhancer experiment description: | Furthermore, in line with the epigenome in DIO mice, palmitate treatment caused increase in H3K27ac and induction of ?-oxidation genes; these responses were blunted when NRF1, GABPA or MEF2A were suppressed. |
About Target gene
| Target gene : | NRF1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Furthermore, in line with the epigenome in DIO mice, palmitate treatment caused increase in H3K27ac and induction of ?-oxidation genes; these responses were blunted when NRF1, GABPA or MEF2A were suppressed. |
About TF
| TF name : | -- |
| TF experiment: | RNA-Seq?ChIP-Seq?qPCR?TSS |
| TF experiment description: | Furthermore, in line with the epigenome in DIO mice, palmitate treatment caused increase in H3K27ac and induction of ?-oxidation genes; these responses were blunted when NRF1, GABPA or MEF2A were suppressed. |
About Function
| Enhancer function : | Furthermore, in line with the epigenome in DIO mice, palmitate treatment caused increase in H3K27ac and induction of ?-oxidation genes; these responses were blunted when NRF1, GABPA or MEF2A were suppressed. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Furthermore, in line with the epigenome in DIO mice, palmitate treatment caused increase in H3K27ac and induction of ?-oxidation genes; these responses were blunted when NRF1, GABPA or MEF2A were suppressed. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene