About Enhancer
| Enhancer ID: | E_02_0408 |
| Species: | mouse |
| Position : | chr2:9838078-9840078   |
| Biosample name: | |
| Experiment class : | Low throughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 30295986 |
| Enhancer experiment: | Luciferase Reporter Assay,qPCR |
| Enhancer experiment description: | We next employed a transient transfection assay to test putative Gata3 Enhancers in Gata3-expressing 293T cells using a heterologous TATA promoter that drives Luciferasegene expression. Here we describe the identification of a novel bipartite Gata3 lens-specific Enhancer located ~18 kb upstream from its transcriptional start site. We also found that a 5 kb Gata3 promoter possesses low activity in the lens. |
About Target gene
| Target gene : | Gata3(Gata-3,jal) |
| Strong evidence: | -- |
| Less strong evidence: | Luciferase Reporter Assay,qPCR |
| Target gene experiment description: | Here we describe the identification of a novel bipartite Gata3 lens-specific enhancer located 18 kb upstream from its transcriptional start site. We also found that a 5-kb Gata3 promoter possesses low activity in the lens. The bipartite enhancer contains arrays of AP-1, Ets-, and Smad1/5-binding sites as well as binding sites for lensassociated DNA-binding factors. |
About TF
| TF name : | -- |
| TF experiment: | -- |
| TF experiment description: | -- |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene