About Enhancer
| Enhancer ID: | E_02_0398 |
| Species: | human |
| Position : | chr6:125744351-125746351   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Alzheimer disease |
| Pubmed ID: | 30365070 |
| Enhancer experiment: | Hematoxylin and eosin (H&E) staining,Immunohistochemistry,TUNEL staining,RT?qPCR,Western blot, |
| Enhancer experiment description: | In conclusion, the results demonstrated that miR-98 reduced the production of A? and improved oxidative stress and mitochondrial dysfunction through activation of the Notch signaling pathway by binding to HEY2 in AD mice. |
About Target gene
| Target gene : | HEY2 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | In conclusion, the results demonstrated that miR-98 reduced the production of A? and improved oxidative stress and mitochondrial dysfunction through activation of the Notch signaling pathway by binding to HEY2 in AD mice. |
About TF
| TF name : | -- |
| TF experiment: | Hematoxylin and eosin (H&E) staining,Immunohistochemistry,TUNEL staining,RT?qPCR,Western blot, |
| TF experiment description: | In conclusion, the results demonstrated that miR-98 reduced the production of A? and improved oxidative stress and mitochondrial dysfunction through activation of the Notch signaling pathway by binding to HEY2 in AD mice. |
About Function
| Enhancer function : | In conclusion, the results demonstrated that miR-98 reduced the production of A? and improved oxidative stress and mitochondrial dysfunction through activation of the Notch signaling pathway by binding to HEY2 in AD mice. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
In conclusion, the results demonstrated that miR-98 reduced the production of A? and improved oxidative stress and mitochondrial dysfunction through activation of the Notch signaling pathway by binding to HEY2 in AD mice. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene