About Enhancer
| Enhancer ID: | E_02_0376 |
| Species: | human |
| Position : | chr7:148804686-148806686   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Brachial plexus avulsion |
| Pubmed ID: | 32346844 |
| Enhancer experiment: | Western Blot?q-RT PCR?Immunofluorescence Analysis |
| Enhancer experiment description: | We found that EZH2 levels were markedly upregulated during BPA-induced neuropathic pain in vivo and in vitro, stimulating pro-inflammatory cytokines (IL- 1b, TNF-a, and IL-6) secretion in vivo. |
About Target gene
| Target gene : | EZH2 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | We found that EZH2 levels were markedly upregulated during BPA-induced neuropathic pain in vivo and in vitro, stimulating pro-inflammatory cytokines (IL- 1b, TNF-a, and IL-6) secretion in vivo. |
About TF
| TF name : | -- |
| TF experiment: | Western Blot?q-RT PCR?Immunofluorescence Analysis |
| TF experiment description: | We found that EZH2 levels were markedly upregulated during BPA-induced neuropathic pain in vivo and in vitro, stimulating pro-inflammatory cytokines (IL- 1b, TNF-a, and IL-6) secretion in vivo. |
About Function
| Enhancer function : | We found that EZH2 levels were markedly upregulated during BPA-induced neuropathic pain in vivo and in vitro, stimulating pro-inflammatory cytokines (IL- 1b, TNF-a, and IL-6) secretion in vivo. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
We found that EZH2 levels were markedly upregulated during BPA-induced neuropathic pain in vivo and in vitro, stimulating pro-inflammatory cytokines (IL- 1b, TNF-a, and IL-6) secretion in vivo. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene