About Enhancer
| Enhancer ID: | E_02_0375 |
| Species: | human |
| Position : | chr1:247412880-247414880   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Neuronal injury |
| Pubmed ID: | 32337955 |
| Enhancer experiment: | Western blotting?Immunohistochemical analysis |
| Enhancer experiment description: | Treatment with melodinhenine B attenuated the altered expression of NF-?B, IL-1?, NLRP3, ZO-1, and occluding proteins in the brain tissue of I/R-induced neuronal injury rats. |
About Target gene
| Target gene : | NLRP3 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Treatment with melodinhenine B attenuated the altered expression of NF-?B, IL-1?, NLRP3, ZO-1, and occluding proteins in the brain tissue of I/R-induced neuronal injury rats. |
About TF
| TF name : | -- |
| TF experiment: | Western blotting?Immunohistochemical analysis |
| TF experiment description: | Treatment with melodinhenine B attenuated the altered expression of NF-?B, IL-1?, NLRP3, ZO-1, and occluding proteins in the brain tissue of I/R-induced neuronal injury rats. |
About Function
| Enhancer function : | Treatment with melodinhenine B attenuated the altered expression of NF-?B, IL-1?, NLRP3, ZO-1, and occluding proteins in the brain tissue of I/R-induced neuronal injury rats. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Treatment with melodinhenine B attenuated the altered expression of NF-?B, IL-1?, NLRP3, ZO-1, and occluding proteins in the brain tissue of I/R-induced neuronal injury rats. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene