About Enhancer
| Enhancer ID: | E_02_0347 |
| Species: | human |
| Position : | chr19:17822384-17824384   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Periodontal disease |
| Pubmed ID: | 32433819 |
| Enhancer experiment: | Western blot,siRNA?Immunoprecipitation?RT-PCR |
| Enhancer experiment description: | Moreover, using gainand loss-of-function approaches, we demonstrate that downstream molecules of Wnt3a signaling, including Dvl3 and ?-catenin, are responsible for the negative regulatory role of Wnt3a. |
About Target gene
| Target gene : | JAK3 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Moreover, using gainand loss-of-function approaches, we demonstrate that downstream molecules of Wnt3a signaling, including Dvl3 and ?-catenin, are responsible for the negative regulatory role of Wnt3a. |
About TF
| TF name : | -- |
| TF experiment: | Western blot,siRNA?Immunoprecipitation?RT-PCR |
| TF experiment description: | Moreover, using gainand loss-of-function approaches, we demonstrate that downstream molecules of Wnt3a signaling, including Dvl3 and ?-catenin, are responsible for the negative regulatory role of Wnt3a. |
About Function
| Enhancer function : | Moreover, using gainand loss-of-function approaches, we demonstrate that downstream molecules of Wnt3a signaling, including Dvl3 and ?-catenin, are responsible for the negative regulatory role of Wnt3a. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Moreover, using gainand loss-of-function approaches, we demonstrate that downstream molecules of Wnt3a signaling, including Dvl3 and ?-catenin, are responsible for the negative regulatory role of Wnt3a. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene