About Enhancer
| Enhancer ID: | E_02_0326 |
| Species: | human |
| Position : | chr17:42310380-42312380   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Neoplasms, thrombosis, inflammation related disorders, obesity |
| Pubmed ID: | 29689351 |
| Enhancer experiment: | MTT,Oil Red O staining,crystal violet staining,flow cytometry,ELISA,Quantitative Real-time PCR, Immunofluorescence,western blot,Immunoblotting, |
| Enhancer experiment description: | GFE inhibits lipogenesis by negative regulation of adipogenic transcription factors, which is associated with GFE-mediated cell cycle arrest and STAT3 inhibition. |
About Target gene
| Target gene : | STAT3(1110034C02Rik,AW109958,Aprf) |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | GFE inhibits lipogenesis by negative regulation of adipogenic transcription factors, which is associated with GFE-mediated cell cycle arrest and STAT3 inhibition. |
About TF
| TF name : | -- |
| TF experiment: | MTT,Oil Red O staining,crystal violet staining,flow cytometry,ELISA,Quantitative Real-time PCR, Immunofluorescence,western blot,Immunoblotting, |
| TF experiment description: | GFE inhibits lipogenesis by negative regulation of adipogenic transcription factors, which is associated with GFE-mediated cell cycle arrest and STAT3 inhibition. |
About Function
| Enhancer function : | GFE inhibits lipogenesis by negative regulation of adipogenic transcription factors, which is associated with GFE-mediated cell cycle arrest and STAT3 inhibition. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
GFE inhibits lipogenesis by negative regulation of adipogenic transcription factors, which is associated with GFE-mediated cell cycle arrest and STAT3 inhibition. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene