About Enhancer
| Enhancer ID: |
E_02_0294 |
| Species: |
mouse |
| Position :
|
chr14:73418621-73420621
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Cystic echinococcosis, a chronic zoonotic disease |
| Pubmed ID: |
29848344
|
| Enhancer experiment: |
Microarray profiling,Quantitative reverse transcription-PCR (qRT-PCR),Cis- and trans-regulation analysis |
| Enhancer experiment description: |
Our study identified dysregulated lncRNAs in the M-MDSCs of E. granulosus infection mouse models; they might be involved in M-MDSC-derived immunosuppression in related diseases. |
About Target gene
| Target gene : |
Rb1(OSRC,PPP1R130,RB,p105-Rb,pRb,pp110) |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Our study identified dysregulated lncRNAs in the M-MDSCs of E. granulosus infection mouse models; they might be involved in M-MDSC-derived immunosuppression in related diseases. |
About TF
| TF name : |
-- |
| TF experiment: |
Microarray profiling,Quantitative reverse transcription-PCR (qRT-PCR),Cis- and trans-regulation analysis |
| TF experiment description: |
Our study identified dysregulated lncRNAs in the M-MDSCs of E. granulosus infection mouse models; they might be involved in M-MDSC-derived immunosuppression in related diseases. |
About Function
| Enhancer function : |
Our study identified dysregulated lncRNAs in the M-MDSCs of E. granulosus infection mouse models; they might be involved in M-MDSC-derived immunosuppression in related diseases. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
Our study identified dysregulated lncRNAs in the M-MDSCs of E. granulosus infection mouse models; they might be involved in M-MDSC-derived immunosuppression in related diseases. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs