About Enhancer
| Enhancer ID: | E_02_0256 |
| Species: | human |
| Position : | chr9:104778131-104780131   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Chronic neurodegenerative diseases |
| Pubmed ID: | 30627958 |
| Enhancer experiment: | Immunohistochemistry staining, PCR, Western blot, immunofluorescence |
| Enhancer experiment description: | In detail, PGA1 activated the peroxisome proliferator-activated receptor-gamma (PPAR?) and ATP-binding cassette subfamily A member 1 (ABCA1) signalling pathways, promoting the efflux of cholesterol and decreasing the intracellular cholesterol levels. |
About Target gene
| Target gene : | ABCA1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | In detail, PGA1 activated the peroxisome proliferator-activated receptor-gamma (PPAR?) and ATP-binding cassette subfamily A member 1 (ABCA1) signalling pathways, promoting the efflux of cholesterol and decreasing the intracellular cholesterol levels. |
About TF
| TF name : | -- |
| TF experiment: | ??????????PCR?Western blot?????? |
| TF experiment description: | In detail, PGA1 activated the peroxisome proliferator-activated receptor-gamma (PPAR?) and ATP-binding cassette subfamily A member 1 (ABCA1) signalling pathways, promoting the efflux of cholesterol and decreasing the intracellular cholesterol levels. |
About Function
| Enhancer function : | In detail, PGA1 activated the peroxisome proliferator-activated receptor-gamma (PPAR?) and ATP-binding cassette subfamily A member 1 (ABCA1) signalling pathways, promoting the efflux of cholesterol and decreasing the intracellular cholesterol levels. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
In detail, PGA1 activated the peroxisome proliferator-activated receptor-gamma (PPAR?) and ATP-binding cassette subfamily A member 1 (ABCA1) signalling pathways, promoting the efflux of cholesterol and decreasing the intracellular cholesterol levels. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene