About Enhancer
| Enhancer ID: |
E_02_0254 |
| Species: |
human |
| Position :
|
chr4:54654587-54656587  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Gastrointestinal stromal tumors |
| Pubmed ID: |
30630822
|
| Enhancer experiment: |
Chip SEQ, RNA SEQ, immunoblotting, cloning, CRISPR assays, PCR |
| Enhancer experiment description: |
In this study, we identify regulatory regions of the KIT enhancer essential for KIT gene expression and GIST cell viability. |
About Target gene
| Target gene : |
KIT(C-Kit,CD117,MASTC,PBT,SCFR) |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
In this study, we identify regulatory regions of the KIT enhancer essential for KIT gene expression and GIST cell viability. |
About TF
| TF name : |
-- |
| TF experiment: |
ChIP-seq?RNA-seq???????Cloning ?CRISPR assays?PCR |
| TF experiment description: |
In this study, we identify regulatory regions of the KIT enhancer essential for KIT gene expression and GIST cell viability. |
About Function
| Enhancer function : |
In this study, we identify regulatory regions of the KIT enhancer essential for KIT gene expression and GIST cell viability. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function experiment description: |
In this study, we identify regulatory regions of the KIT enhancer essential for KIT gene expression and GIST cell viability. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs