About Enhancer
| Enhancer ID: | E_02_0207 |
| Species: | human |
| Position : | chr4:77508709-77510709   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Systemic lupus erythematosus |
| Pubmed ID: | 31546763 |
| Enhancer experiment: | Western blot,PCR,Flow cytometry |
| Enhancer experiment description: | During the disease state, this subset of mDCs displayed heightened toll-like receptors 7 and 9 (TLR 7/9) responses with increased interleukin 10 (IL-10) and C-X-C motif chemokine ligand 13 (CXCL13) expressions. |
About Target gene
| Target gene : | CXCL13(ANGIE,ANGIE2,BCA-1,BCA1,BLC,BLR1L,SCYB13) |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | During the disease state, this subset of mDCs displayed heightened toll-like receptors 7 and 9 (TLR 7/9) responses with increased interleukin 10 (IL-10) and C-X-C motif chemokine ligand 13 (CXCL13) expressions. |
About TF
| TF name : | -- |
| TF experiment: | Western blot,PCR,Flow cytometry |
| TF experiment description: | During the disease state, this subset of mDCs displayed heightened toll-like receptors 7 and 9 (TLR 7/9) responses with increased interleukin 10 (IL-10) and C-X-C motif chemokine ligand 13 (CXCL13) expressions. |
About Function
| Enhancer function : | During the disease state, this subset of mDCs displayed heightened toll-like receptors 7 and 9 (TLR 7/9) responses with increased interleukin 10 (IL-10) and C-X-C motif chemokine ligand 13 (CXCL13) expressions. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
During the disease state, this subset of mDCs displayed heightened toll-like receptors 7 and 9 (TLR 7/9) responses with increased interleukin 10 (IL-10) and C-X-C motif chemokine ligand 13 (CXCL13) expressions. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene