About Enhancer
| Enhancer ID: | E_02_0182 |
| Species: | human |
| Position : | chr1:204393890-204395890   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Diabetes |
| Pubmed ID: | 31615341 |
| Enhancer experiment: | Flow cytometry,PCR,Western blot |
| Enhancer experiment description: | However, levels of TGF?R1 did not show any change and therefore is possibly not a direct target of miR-98-5p. miR-98-5p also significantly decreased the mRNA levels of PPP1R15B (Figure 3(b)) further suggesting that this gene is targeted by miR-98-5p. |
About Target gene
| Target gene : | PPP1R15B |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | However, levels of TGF?R1 did not show any change and therefore is possibly not a direct target of miR-98-5p. miR-98-5p also significantly decreased the mRNA levels of PPP1R15B (Figure 3(b)) further suggesting that this gene is targeted by miR-98-5p. |
About TF
| TF name : | -- |
| TF experiment: | Flow cytometry,PCR,Western blot |
| TF experiment description: | However, levels of TGF?R1 did not show any change and therefore is possibly not a direct target of miR-98-5p. miR-98-5p also significantly decreased the mRNA levels of PPP1R15B (Figure 3(b)) further suggesting that this gene is targeted by miR-98-5p. |
About Function
| Enhancer function : | However, levels of TGF?R1 did not show any change and therefore is possibly not a direct target of miR-98-5p. miR-98-5p also significantly decreased the mRNA levels of PPP1R15B (Figure 3(b)) further suggesting that this gene is targeted by miR-98-5p. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
However, levels of TGF?R1 did not show any change and therefore is possibly not a direct target of miR-98-5p. miR-98-5p also significantly decreased the mRNA levels of PPP1R15B (Figure 3(b)) further suggesting that this gene is targeted by miR-98-5p. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene