About Enhancer
| Enhancer ID: | E_02_0176 |
| Species: | human |
| Position : | chr16:72780389-72782389   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Arrhythmia |
| Pubmed ID: | 31628324 |
| Enhancer experiment: | Flow cytometry,PCR |
| Enhancer experiment description: | A third locus we examined is 16q22. The most highly AF_x0002_associated risk SNPs in this locus are found in the first intron of ZFHX3, which codes for a TF that plays key roles in development and in adult tissues56,57. |
About Target gene
| Target gene : | ZFHX3 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | A third locus we examined is 16q22. The most highly AF_x0002_associated risk SNPs in this locus are found in the first intron of ZFHX3, which codes for a TF that plays key roles in development and in adult tissues56,57. |
About TF
| TF name : | -- |
| TF experiment: | Flow cytometry,PCR |
| TF experiment description: | A third locus we examined is 16q22. The most highly AF_x0002_associated risk SNPs in this locus are found in the first intron of ZFHX3, which codes for a TF that plays key roles in development and in adult tissues56,57. |
About Function
| Enhancer function : | A third locus we examined is 16q22. The most highly AF_x0002_associated risk SNPs in this locus are found in the first intron of ZFHX3, which codes for a TF that plays key roles in development and in adult tissues56,57. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
A third locus we examined is 16q22. The most highly AF_x0002_associated risk SNPs in this locus are found in the first intron of ZFHX3, which codes for a TF that plays key roles in development and in adult tissues56,57. |
About SNP
| SNP ID: | rs281766 |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene