About Enhancer
| Enhancer ID: | E_02_0158 |
| Species: | human |
| Position : | chrX:73818246-73820246   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Cancer |
| Pubmed ID: | 31665646 |
| Enhancer experiment: | Flow cytometry,PCR |
| Enhancer experiment description: | HEK293 are female cells and, therefore, one of the two X chromosomes is subject to X chromosome inactivation, a process that is dependent on the expression of the XIST lncRNA (da Rocha and Heard, 2017; Jgu et al., 2017). Both MapR and RH?C&R signals are clearly higher than the respective controls at the 5? end of the XIST gene (Figure 2E). |
About Target gene
| Target gene : | XIST |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | HEK293 are female cells and, therefore, one of the two X chromosomes is subject to X chromosome inactivation, a process that is dependent on the expression of the XIST lncRNA (da Rocha and Heard, 2017; Jgu et al., 2017). Both MapR and RH?C&R signals are clearly higher than the respective controls at the 5? end of the XIST gene (Figure 2E). |
About TF
| TF name : | -- |
| TF experiment: | Flow cytometry,PCR |
| TF experiment description: | HEK293 are female cells and, therefore, one of the two X chromosomes is subject to X chromosome inactivation, a process that is dependent on the expression of the XIST lncRNA (da Rocha and Heard, 2017; Jgu et al., 2017). Both MapR and RH?C&R signals are clearly higher than the respective controls at the 5? end of the XIST gene (Figure 2E). |
About Function
| Enhancer function : | HEK293 are female cells and, therefore, one of the two X chromosomes is subject to X chromosome inactivation, a process that is dependent on the expression of the XIST lncRNA (da Rocha and Heard, 2017; Jgu et al., 2017). Both MapR and RH?C&R signals are clearly higher than the respective controls at the 5? end of the XIST gene (Figure 2E). |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
HEK293 are female cells and, therefore, one of the two X chromosomes is subject to X chromosome inactivation, a process that is dependent on the expression of the XIST lncRNA (da Rocha and Heard, 2017; Jgu et al., 2017). Both MapR and RH?C&R signals are clearly higher than the respective controls at the 5? end of the XIST gene (Figure 2E). |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene