About Enhancer
| Enhancer ID: | E_02_0087 |
| Species: | human |
| Position : | chr8:144311848-144313848   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 29556394 |
| Enhancer experiment: | Proliferation study,Differentiation study,Differentiation study,Cytochemical staining |
| Enhancer experiment description: | Treatment with BA modulated the expression of adipocytic differentiation markers: peroxisome proliferator-activated receptor ? and CCAAT/enhancer binding protein ? were significantly increased by both BA-2.5 and BA-5 throughout the study, while lipoprotein lipase and fatty acid-binding protein 4 were increased by BA-5 at day 3, and decreased by both BA-5 and BA- 2.5 later throughout the study. |
About Target gene
| Target gene : | DGAT1,FAS,CPT2 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Treatment with BA modulated the expression of adipocytic differentiation markers: peroxisome proliferator-activated receptor ? and CCAAT/enhancer binding protein ? were significantly increased by both BA-2.5 and BA-5 throughout the study, while lipoprotein lipase and fatty acid-binding protein 4 were increased by BA-5 at day 3, and decreased by both BA-5 and BA- 2.5 later throughout the study.;Treatment with BA modulated the expression of adipocytic differentiation markers: peroxisome proliferator-activated receptor ? and CCAAT/enhancer binding protein ? were significantly increased by both BA-2.5 and BA-5 throughout the study, while lipoprotein lipase and fatty acid-binding protein 4 were increased by BA-5 at day 3, and decreased by both BA-5 and BA- 2.5 later throughout the study.;Treatment with BA modulated the expression of adipocytic differentiation markers: peroxisome proliferator-activated receptor ? and CCAAT/enhancer binding protein ? were significantly increased by both BA-2.5 and BA-5 throughout the study, while lipoprotein lipase and fatty acid-binding protein 4 were increased by BA-5 at day 3, and decreased by both BA-5 and BA- 2.5 later throughout the study. |
About TF
| TF name : | -- |
| TF experiment: | Proliferation study,Differentiation study,Differentiation study,Cytochemical staining |
| TF experiment description: | Treatment with BA modulated the expression of adipocytic differentiation markers: peroxisome proliferator-activated receptor ? and CCAAT/enhancer binding protein ? were significantly increased by both BA-2.5 and BA-5 throughout the study, while lipoprotein lipase and fatty acid-binding protein 4 were increased by BA-5 at day 3, and decreased by both BA-5 and BA- 2.5 later throughout the study.;Treatment with BA modulated the expression of adipocytic differentiation markers: peroxisome proliferator-activated receptor ? and CCAAT/enhancer binding protein ? were significantly increased by both BA-2.5 and BA-5 throughout the study, while lipoprotein lipase and fatty acid-binding protein 4 were increased by BA-5 at day 3, and decreased by both BA-5 and BA- 2.5 later throughout the study.;Treatment with BA modulated the expression of adipocytic differentiation markers: peroxisome proliferator-activated receptor ? and CCAAT/enhancer binding protein ? were significantly increased by both BA-2.5 and BA-5 throughout the study, while lipoprotein lipase and fatty acid-binding protein 4 were increased by BA-5 at day 3, and decreased by both BA-5 and BA- 2.5 later throughout the study. |
About Function
| Enhancer function : | Treatment with BA modulated the expression of adipocytic differentiation markers: peroxisome proliferator-activated receptor ? and CCAAT/enhancer binding protein ? were significantly increased by both BA-2.5 and BA-5 throughout the study, while lipoprotein lipase and fatty acid-binding protein 4 were increased by BA-5 at day 3, and decreased by both BA-5 and BA- 2.5 later throughout the study. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Treatment with BA modulated the expression of adipocytic differentiation markers: peroxisome proliferator-activated receptor ? and CCAAT/enhancer binding protein ? were significantly increased by both BA-2.5 and BA-5 throughout the study, while lipoprotein lipase and fatty acid-binding protein 4 were increased by BA-5 at day 3, and decreased by both BA-5 and BA- 2.5 later throughout the study. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene