About Enhancer
| Enhancer ID: |
E_02_0052 |
| Species: |
human |
| Position :
|
chr2:233757381-233759381
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Hepatic fibrosis |
| Pubmed ID: |
31980500
|
| Enhancer experiment: |
QRT PCR, Western blot, glucuronidation assay, transfection, chromatin immunoprecipitation assay, agarose gel electrophoresis |
| Enhancer experiment description: |
An LXR specific enhancer site on the UGT1A1 gene was identified, along with convincing evidence that LXR? is crucial in maintaining constitutive expression of UGT1A1 in adult hUGT1 mice. |
About Target gene
| Target gene : |
UGT1A1(BILIQTL1,GNT1,HUG-BR1,UDPGT,UDPGT1-1,UGT1,UGT1A) |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
An LXR specific enhancer site on the UGT1A1 gene was identified, along with convincing evidence that LXR? is crucial in maintaining constitutive expression of UGT1A1 in adult hUGT1 mice. |
About TF
| TF name : |
-- |
| TF experiment: |
qRT-PCR?Western Blot?????????????????????????????? |
| TF experiment description: |
An LXR specific enhancer site on the UGT1A1 gene was identified, along with convincing evidence that LXR? is crucial in maintaining constitutive expression of UGT1A1 in adult hUGT1 mice. |
About Function
| Enhancer function : |
An LXR specific enhancer site on the UGT1A1 gene was identified, along with convincing evidence that LXR? is crucial in maintaining constitutive expression of UGT1A1 in adult hUGT1 mice. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
An LXR specific enhancer site on the UGT1A1 gene was identified, along with convincing evidence that LXR? is crucial in maintaining constitutive expression of UGT1A1 in adult hUGT1 mice. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs