About Enhancer
| Enhancer ID: | E_02_0049 |
| Species: | human |
| Position : | chr22:39517640-39519640   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Spinal cord injury |
| Pubmed ID: | 26842780 |
| Enhancer experiment: | Western blot,RT-PCR |
| Enhancer experiment description: | While suppressing general protein translation, eIF2? phosphorylation also promotes the selective translation of some mRNAs, such as ATF4 that induces CCAAT/enhancer binding homologous protein (CHOP), a pro-apoptotic transcription factor. |
About Target gene
| Target gene : | ATF4 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | While suppressing general protein translation, eIF2? phosphorylation also promotes the selective translation of some mRNAs, such as ATF4 that induces CCAAT/enhancer binding homologous protein (CHOP), a pro-apoptotic transcription factor. |
About TF
| TF name : | -- |
| TF experiment: | Western blot,RT-PCR |
| TF experiment description: | While suppressing general protein translation, eIF2? phosphorylation also promotes the selective translation of some mRNAs, such as ATF4 that induces CCAAT/enhancer binding homologous protein (CHOP), a pro-apoptotic transcription factor. |
About Function
| Enhancer function : | While suppressing general protein translation, eIF2? phosphorylation also promotes the selective translation of some mRNAs, such as ATF4 that induces CCAAT/enhancer binding homologous protein (CHOP), a pro-apoptotic transcription factor. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
While suppressing general protein translation, eIF2? phosphorylation also promotes the selective translation of some mRNAs, such as ATF4 that induces CCAAT/enhancer binding homologous protein (CHOP), a pro-apoptotic transcription factor. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene