About Enhancer
| Enhancer ID: | E_02_0045 |
| Species: | human |
| Position : | chr9:81580972-81582972   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Diabetes mellitus |
| Pubmed ID: | 28744818 |
| Enhancer experiment: | Western Blot,RT-PCR,Dual-luciferase reporter assay |
| Enhancer experiment description: | Subsequently, TLE1, through the transcriptional suppression on expression of Hes1, contributes to the aberrant differentiation of IECs in DM mice |
About Target gene
| Target gene : | TLE1,Hes1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Subsequently, TLE1, through the transcriptional suppression on expression of Hes1, contributes to the aberrant differentiation of IECs in DM mice;Subsequently, TLE1, through the transcriptional suppression on expression of Hes1, contributes to the aberrant differentiation of IECs in DM mice |
About TF
| TF name : | -- |
| TF experiment: | Western Blot,RT-PCR,Dual-luciferase reporter assay |
| TF experiment description: | Subsequently, TLE1, through the transcriptional suppression on expression of Hes1, contributes to the aberrant differentiation of IECs in DM mice;Subsequently, TLE1, through the transcriptional suppression on expression of Hes1, contributes to the aberrant differentiation of IECs in DM mice |
About Function
| Enhancer function : | Subsequently, TLE1, through the transcriptional suppression on expression of Hes1, contributes to the aberrant differentiation of IECs in DM mice |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Subsequently, TLE1, through the transcriptional suppression on expression of Hes1, contributes to the aberrant differentiation of IECs in DM mice |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene