About Enhancer
| Enhancer ID: | E_02_0038 |
| Species: | human |
| Position : | chr12:54572339-54574339   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Ewing sarcoma |
| Pubmed ID: | 29059150 |
| Enhancer experiment: | qRTPCR,ChIP-Seq,Luciferase reporter assay |
| Enhancer experiment description: | We found that PPP1R1A is one of the top ranked target genes of EWS/FLI, the master regulator of ES, and is upregulated by EWS/FLI via a GGAA microsatellite enhancer element |
About Target gene
| Target gene : | PPP1R1A |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | We found that PPP1R1A is one of the top ranked target genes of EWS/FLI, the master regulator of ES, and is upregulated by EWS/FLI via a GGAA microsatellite enhancer element |
About TF
| TF name : | -- |
| TF experiment: | qRTPCR,ChIP-Seq,Luciferase reporter assay |
| TF experiment description: | We found that PPP1R1A is one of the top ranked target genes of EWS/FLI, the master regulator of ES, and is upregulated by EWS/FLI via a GGAA microsatellite enhancer element |
About Function
| Enhancer function : | We found that PPP1R1A is one of the top ranked target genes of EWS/FLI, the master regulator of ES, and is upregulated by EWS/FLI via a GGAA microsatellite enhancer element |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
We found that PPP1R1A is one of the top ranked target genes of EWS/FLI, the master regulator of ES, and is upregulated by EWS/FLI via a GGAA microsatellite enhancer element |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene