About Enhancer
| Enhancer ID: | E_02_0023 |
| Species: | mouse |
| Position : | chr13:116431913-116433913   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Diabete |
| Pubmed ID: | 29220426 |
| Enhancer experiment: | Western blot,Luciferase Reporter Assay,qRT-PCR |
| Enhancer experiment description: | Insulin enhancer binding protein-1 (Isl1), a member of the LIM-homeodomain family, is a well-known activator of the insulin gene (14,15) and is essential for the development of the pancreas (16). |
About Target gene
| Target gene : | Isl1(ISLET1,Isl-1) |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Insulin enhancer binding protein-1 (Isl1), a member of the LIM-homeodomain family, is a well-known activator of the insulin gene (14,15) and is essential for the development of the pancreas (16). |
About TF
| TF name : | -- |
| TF experiment: | Western blot,Luciferase Reporter Assay,qRT-PCR |
| TF experiment description: | Insulin enhancer binding protein-1 (Isl1), a member of the LIM-homeodomain family, is a well-known activator of the insulin gene (14,15) and is essential for the development of the pancreas (16). |
About Function
| Enhancer function : | Insulin enhancer binding protein-1 (Isl1), a member of the LIM-homeodomain family, is a well-known activator of the insulin gene (14,15) and is essential for the development of the pancreas (16). |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Insulin enhancer binding protein-1 (Isl1), a member of the LIM-homeodomain family, is a well-known activator of the insulin gene (14,15) and is essential for the development of the pancreas (16). |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene