About Enhancer
| Enhancer ID: | E_02_0005 |
| Species: | mouse |
| Position : | chr9:123505056-123507056   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Thymus homing |
| Pubmed ID: | 29343500 |
| Enhancer experiment: | Western blot,ChIP-seq,RNA-seq |
| Enhancer experiment description: | Furthermore, cbf?2 endows extrathymic progenitors with thymus-homing capacity by inducing expression of the principal thymus-homing receptor, ccr9. |
About Target gene
| Target gene : | Ccr9,Cbfb |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Furthermore, cbf?2 endows extrathymic progenitors with thymus-homing capacity by inducing expression of the principal thymus-homing receptor, ccr9.;Cbf? forms transcription factor complexes with runx proteins, and here we show that cbf?2, encoded by an rnA splice variant of the cbfb gene, is essential for extrathymic differentiation of t cell progenitors. |
About TF
| TF name : | -- |
| TF experiment: | Western blot,ChIP-seq,RNA-seq |
| TF experiment description: | Furthermore, cbf?2 endows extrathymic progenitors with thymus-homing capacity by inducing expression of the principal thymus-homing receptor, ccr9.;Cbf? forms transcription factor complexes with runx proteins, and here we show that cbf?2, encoded by an rnA splice variant of the cbfb gene, is essential for extrathymic differentiation of t cell progenitors. |
About Function
| Enhancer function : | Furthermore, cbf?2 endows extrathymic progenitors with thymus-homing capacity by inducing expression of the principal thymus-homing receptor, ccr9. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Furthermore, cbf?2 endows extrathymic progenitors with thymus-homing capacity by inducing expression of the principal thymus-homing receptor, ccr9. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene