About Enhancer
| Enhancer ID: | E_02915 |
| Species: | Mus musculus |
| Position : | chr11:44390342-44392251   |
| Year: | 2011 |
| Title: | A distal enhancer in Il12b is the target of transcriptional repression by the STAT3 pathway and requires the basic leucine zipper (B-ZIP) protein NFIL3. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Autoimmune and Inflammatory Diseases |
| PMID: | 21566115 |
| Tissue: | blood / hematopoietic system |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Myeloid Cells,T Cell |
| Cell Type: | T cell |
| Cell Ontology ID: | CL:0000084 |
| Experiment Type: | Enhancer activity assay; Disease-associated enhancer analysis |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; RT-qPCR/qPCR |
About Target Gene
| Target gene : | Il12b |
About TF
| TF name : | Nfil3 |
About Regulatory State
| Regulatory State : | Repressed |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer