Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02632
Species: Mus musculus
Position : chr4:147962887-147964479
Year: 2014
Title: Noninvasive and quantitative live imaging reveals a potential stress-responsive enhancer in the failing heart.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  24391132
Tissue: heart
Tissue Ontology ID: UBERON:0000948
Cell Source: 293T
CVCL ID: CVCL_0063
Experiment Type: Enhancer activity assay; TF-binding/chromatin assay; Chromatin interaction assay; In vivo functional validation
High Throughput Method: ChIP-seq
Low Throughput Method: Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; 3C; Transgenic/LacZ assay
About Target Gene
Target gene : Nppb
About TF
TF name : Ctcf
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Ctcf Activation of anterior HOX genes in hindbrain development during early embryogenesis reactome 120
Ctcf TGF_beta_Receptor netpath 220
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_04030 chr4:147122070-148025142 embryo mouse embryonic stem cell NA
E_02633 chr4:147962887-147964479 heart NA NA
Expression of Target Genes for the Enhancer